суббота, 15 марта 2014 г.

The Shocking Ingredients In Beer

 

I have to confess, I’m not a beer drinker, but there’s someone in my household that loves it, so I had to figure out the truth. Is beer really healthy? Why are the ingredients not listed on the label? Which brands can we trust? Which brands are trying to slowly poison us with cheap and harmful ingredients? All of these questions were going through my head at once at lightning speed. So a year ago, I started to research what was really in beer and after questioning several beer companies, reading books about food science, and talking to experts, the information I discovered was downright shocking.
I see it all the time. Someone who eats organic, makes the right choices at the grocery store, is fit and lives an extraordinarily healthy lifestyle but then drinks beer like it is going out of style.
Caring about what you eat doesn’t necessarily translate into caring about what you drink and this is a HUGE MISTAKE.
Before we get into what exactly is in beer that you should be worried about, let’s talk about how body reacts to alcohol in general.
Alcohol is metabolized by the body differently than all other calories you consume. Alcohol is one of the only substances that you consume that can permeate your digestive system and go straight into your bloodstream. It bypasses normal digestion and is absorbed into the body intact, where it goes straight into the liver.
Your liver is your main fat-burning organ. If you are trying to lose weight or even maintain your ideal weight, drinking alcohol is one of your worst enemies. The liver is going to metabolize alcohol first vs. the fat you want to get rid of – making weight loss even harder. Additionally, one of the primary functions of the liver is to remove environmental toxins from your body – if it is overtaxed with alcohol, the normal removal of these toxins becomes extremely diminished and can result in rapid aging, loss of libido, and other diseases.
The one thing that has gotten me before and I’m sure many of you – is the health marketing claims on alcohol products making drinking them seem like a good idea and an added “benefit” to your health. The low alcohol content of beer makes it appear as an innocuous beverage and something people throw back without even thinking about it. Who hasn’t seen those studies that say a beer a day is great for you (I want to ask who ever stops at just one beer?)?
So, inherently, alcohol by itself is not a healthy person’s best friend – but that’s just the tip of the iceberg.  Beer, especially American beer, is made with all sorts of ingredients beyond the basic hops, malt and yeast. There are numerous other ingredients used to clarify, stabilize, preserve, enhance the color and flavor of beer.
When you drink beer, there is almost a 100% chance that you don’t know what you are drinking (unless you quizzed the beer companies like I did). The ingredients in beer are not required by law to be listed anywhere on the label and manufacturers have no legal obligation to disclose the ingredients. For regular beer, calorie levels and percent alcohol are optional and for light beer calories are mandatory but alcohol levels are optional.
Michele Simon, a public health lawyer, author of Appetite for Profit, and president of Eat Drink Politics told me the reason that beer companies don’t disclose ingredients is simple: they don’t have to.
“Ingredient labeling on food products and non-alcoholic beverages is required by the Food and Drug Administration. But a whole other federal agency regulates beer, and not very well. The Department of Treasury – the same folks who collect your taxes – oversees alcoholic beverages. That probably explains why we know more about what’s in a can of Coke than a can of Bud. You can also thank the alcohol industry, which has lobbied for years against efforts to require ingredient labeling.”
I figured if the beer companies aren’t required to tell us the exact list of ingredients, I needed to investigate this for myself and asked them the pointed questions until I got the truth.
Slide1
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First of all, I was able to obtain a baseline list of “legal” additives allowed in beer from the book “Chemicals Additives in Beer” by the Center of Science and Public Interest. This list allowed me to ask specific questions about each beer I investigated. For example – beer sold here in America can contain several of the following ingredients:
  • Monosodium Glutamate (MSG) –  alcohol is already addictive with some people, but with MSG?! Holy smokes.
  • Propylene Glycol (an ingredient found in anti-freeze)
  • Calcium Disodium EDTA (made from formaldehyde, sodium cayanide, and Ethylenediamine)
  • Many different types of sulfites and anti-microbial preservatives (linked to allergies and asthma)
  • Natural Flavors (can come from anything natural including a beavers anal gland)
  • High Fructose Corn Syrup
  • GMO Sugars – Dextrose, Corn Syrup
  • Caramel Coloring (Class III or IV made from ammonia and classified as a carcinogen)
  • FD&C Blue 1 (Made from petroleum, linked to allergies, asthma and hyperactivity)
  • FD&C Red 40 (Made from petroleum, linked to allergies, asthma and hyperactivity)
  • FD&C Yellow 5 (Made from petroleum, linked to allergies, asthma and hyperactivity)
  • Insect-Based Dyes: carmine derived from cochineal insects to color their beer.
  • Animal Based Clarifiers: Findings include isinglass (dried fish bladder), gelatin (from skin, connective tissue, and bones), and casein (found in milk)
  • Foam Control: Used for head retention; (glyceryl monostearate and pepsin are both potentially derived from animals)
  • BPA (Bisphenol A is a component in many can liners and it may leach into the beer. BPA can mimic the female hormone estrogen and may affect sperm count, and other organ functions.)
  • Carrageenan (linked to inflammation in digestive system, IBS and considered a carcinogen in some circumstances)
During my investigation, I couldn’t get a single mainstream beer company to share the full list of ingredients contained in their beer. But I did get some of them to fess up to the use of these ingredients in writing so I’m going to share this information with you now.
Carcinogenic Caramel Coloring
Newcastle, a UK brand, confessed to using what I would consider one of the most controversial food additives. Toasted barley is usually what gives beer its golden or deep brown color, however in this case, Newcastle beer is also colored artificially with caramel color. This caramel coloring is manufactured by heating ammonia and sulfites under high pressure, which creating carcinogenic compounds. If beer companies were required by law to list the ingredients, Newcastle would likely have to have a cancer warning label under California law because it is a carcinogen proven to cause liver tumors, lung tumors, and thyroid tumors in rats and mice.
Genetically Modified Organisms (GMOs)
Many of the beers I questioned contained one or more possible GMO ingredients.
  • High Fructose Corn Syrup (Guinness – unable to provide an affidavit for non-GMO proof)
  • Corn syrup (Miller Light, Coors, Corona, Fosters, Pabst Blue Ribbon, Red Stripe)
  • Dextrose (Budweiser, Bud Light, Busch Light, Michelob Ultra)
  • Corn (Red Stripe, Miller Coors Brand, Anheuser-Busch Brands)
Most beers brewed commercially are made with more GMO corn than barley. Many of the companies I contacted dodged the GMO question – however Miller Coors had a very forthcoming and honest response. They stated “Corn syrup gives beer a milder and lighter-bodied flavor” and “Corn syrups may be derived from a mixture of corn (conventional and biotech.)”, admitting their use of GMOs.
Slide2
Pabst Blue Ribbon responded saying their corn syrup was “special” and “made of carbohydrates and some simple sugars like dextrose and maltose.  The sugars are fermented into alcohol and CO2, and the carbohydrates, both from the corn syrup and the malt, remain in the beers as flavor, color and body components.”
Dextrose and maltose can come from a variety of substances that are sweet, but likely are derived from GMO corn because it is super cheap for a company to use corn instead of fruit or other non-GMO sources. With cheap beer – you are not just getting a cheap buzz, you are getting the worst of the worst.  Just like with cheap fast food – if you don’t invest in your beer – you will be drinking a lower quality product like Pabst Blue Ribbon that is made from GMO Corn and Corn Syrup.
In 2007, Greenpeace found unapproved and experimental GMO Rice strain in Anheuser-Busch (Budweiser, Bud Light) beer. Anheuser-Busch responded saying their US-grown long-grained rice “may have micro levels” of a genetically engineered protein called Liberty Link, but added that the protein is “substantially removed or destroyed” during the brewing of beer sold domestically. Don’t you think it’s hard to trust any beer company that gets caught using experimental food made in a laboratory? GMOs have not been tested long term on human beings and one of the main pesticides (Roundup) they spray on GMO crops are linked to inflammation, cancer and other diseases. 
Guinness
High Fructose Corn Syrup & Fish Bladders
Speaking of trusting companies, let’s get one thing straight, Guinness beer is no longer owned by the Irish, they are now owned by a large beer conglomerate called Diageo and manufactured in over 50 different countries. No matter how many St. Patty’s Day celebrations you’ve had with this dark stout, it’s time to stop because they use high fructose corn syrup in their beer. But, Guinness beer also contains isinglass, a gelatin-like substance produced from the swim bladder of a fish. This ingredient helps remove any “haziness,” solids, or yeast byproducts from the beer. Mmmmm… fish bladder sounds delicious, doesn’t? The sneaky thing this beer company does like many of the companies mentioned here today is create an illusion of using the best ingredients when in actuality what they tell you publicly on their websites is a complete farce. On Guinness FAQ’s – they have a question that states: “What are the key ingredients in Guinness” and the answer doesn’t reveal the whole picture – it only states “Our key ingredients – other than inspiration – are roasted, malted barley, hops, yeast and water.” What BS, right?  You have to call, email, question and know the right things to ask to even have a chance at getting the truth. This is insanity.
So What Beers Are Additive and GMO Free?
If you enjoy the occasional beer and wish to maintain your healthy lifestyle, choosing one without GMOs and additives is ideal. Unfortunately, most of the mainstream beers available have additives, but luckily, there are a few that don’t. For example, Sierra Nevada, Heineken, and Amstel Light (7/31 UPDATE: It has come to my attention that Heinken USA has changed their formula to use GMOs – I called their customer service line 1-914-681-4100 to confirm and asked for the list of ingredients – the man told me “water, yeast, malted barley and hops” – then I asked if their beer contained any genetically engineered material and he confirmed “YES,” but wouldn’t tell me what ingredients are genetically engineered. They recently changed their formula after my initial research that started in late 2012.) (8/1 Update: Heineken reached out to me personally to say their customer service department made an error in telling me and others who called their beer has GMOs. I met with a head brew master and have viewed affidavits from the company and confirmed Heinken and Amstel Light do not contain GMOs – they apologize for the confusion.) appear to be pretty clean (but these companies still wouldn’t disclose the full list of ingredients to me. They did say they use non-GMO grains, no artificial ingredients, stabilizers or preservatives).
German Beers are also a good bet. The Germans are very serious about the purity of their beers and enacted a purity law called “Reinheitsgebot” that requires all German beers to be only produced with a core ingredient list of water, hops, yeast, malted barley or wheat. Advocates of German beers insist that they taste cleaner and some even claim they don’t suffer from hangovers as a result.
An obvious choice to consider is also Certified Organic Beers. They are required by law to not include GMOs and other harmful additives. Organic beers also support environmental friendly practices and reduce the amount of pesticides and toxins in our air, support organic farmers – which is a huge plus. (To this day, the beer drinkers in my family haven’t found one they love so if you have suggestions, please let us know in the comments!)
Craft & Microbrews Beers – For certain local craft and micro beers, you can ask those companies for a list of ingredients and many of them will be up front with you. However, companies like Miller Coors are slowly closing in on craft beers and buying them up one by one… like they did when they created the unique popular variety called Blue Moon (the beer you drink with an orange) and Anhesuer-Busch did this with Rolling Rock and Goose Island Brewery. Make sure your favorite craft and microbrew is still independently owned and controlled before taking a sip.
In the end – if you decide to drink beer, you are definitely drinking at your own risk for more reasons than just the crazy ingredients that could be in them. The key point to remember is – if you like to drink beer and want to be healthy, drink it infrequently and quiz the beer companies for the truth. Find a beer that you can trust and stick with it.
For your reference, here are some important questions to ask your favorite beer company:
  1. What are the ingredients in your beer – all of them from start to finish?
  2. Are any of your ingredients GMO?
  3. Do you use any soy, corn, or rice processing ingredients? (Examples include: dextrose, corn syrup, etc.)
  4. Do you add any natural, artificial flavors or colors to the beer? (Examples include:  yellow #5, caramel coloring, red #40, MSG, natural flavors)
  5. Are there any additional preservatives, stabilizers and/or clarifying agents added to your beer during processing? (Examples include: propylene glycol, Calcium Disodium EDTA, anything ending in “sulfite” like sodium metabisulfite, Heptylparaben, isinglass)
If you know someone who drinks beer – share this post with them.
These ingredients are no joke. We must inform and protect each other from these industrial chemicals, untested and potentially harmful ingredients and it starts by sharing your knowledge with the ones you love.
Bottoms up!
http://foodbabe.com/2013/07/17/the-shocking-ingredients-in-beer/

витамин Е

В российских женских консультациях рекомендации по приему витамина Е выглядят следующим образом: принимать витамин Е по 1 капсуле 3 раза в день. А ведь выпускаются капсулы с дозировкой 100, 200 и даже 400 мг, в то время, как суточная потребность в витамине Е составляет всего 0,3 мг/кг, то есть, женщине с весом 60 кг необходимо всего 18 мг витамина Е в сутки, которые она может получить с пищей.

P.S. В 2009 году голландцы опубликовали исследование, в котором оценивалось влияние потребления витамина Е при беременности на риск развития пороков сердца у новорожденных. Оказалось, что потребление с пищей

витамина Е выше 12,6 мг/день одновременно с дополнительным приемом витамина Е в капсулах увеличивает в 5-9 раз риск развития пороков сердца у детей. Причем этот риск не снижался при добавлении к витамину Е фолиевой кислоты.

Папаверин и его производные




-Папаверин
ПАПАВЕРИН,
ПАПАВЕРИН-ДАРНИЦА,
ПАПАВЕРИН-ЗДОРОВЬЕ,
ПАПАВЕРИНА ГИДРОХЛОРИД,

-Дротаверин

ДРОТАВЕРИН,
ДРОТАВЕРИН ФОРТЕ,
ДРОТАВЕРИН-ДАРНИЦА,
ДРОТАВЕРИНА ГИДРОХЛОРИД,
НО-Х-ША®,
НО-Х-ША® ФОРТЕ,
НО-ШПА®,
НОХШАВЕРИН "ОЗ",

пятница, 14 марта 2014 г.

Fish Oil- Decreases Fat & Increases Lean Body Mass

 


fishoilConsuming fish or Omega-3-rich fish oil is a sure way to lose weight slowly but consistently. Fish oil makes you "look good and feel good." The key to weight loss is to lose fat one pound at a time. Small changes in weight won't give you a killer body right away. The accumulation of many small changes over time makes a huge impact. Most people won't do the work it takes to lose a lot of weight, let alone devote any effort to small, barely noticeable changes. Added up, many small changes in weight make major differences in how you look and feel. To be practical, small changes should be inexpensive, automatic, and near-effortless. Fish oil fits the bill!

The goal of bodybuilding mirrors that of every frustrated office worker, teacher, and homemaker- to drop fat and tone muscle. Daily fish oil supplements, or eating fish frequently, helps cut body fat. Even better, fish oil promotes abdominal fat loss. Gut fat is linked to heart disease, diabetes, abnormal blood fats, and high blood pressure.

A recent study published in the Journal of the International Society of Sports Nutrition investigated the effect of fish oil supplements on healthy male and female adults. The fish oil supplements contained 1,600 milligrams of EPA and 800 milligrams of DHA. After six weeks, the fish oil decreased fat and cortisol (a stress hormone) and increased muscle mass. Fish oil caused a slight increase in caloric expenditure and fat burning compared to a placebo (fake fish oil).

Consuming just two fish oil capsules with breakfast and dinner will decrease body fat and increase lean mass, which will make you look better and feel healthier. In other words, fish oil causes small but noticeable differences in making you look and feel better. The absolute differences were small. The fish oil-treated subjects lost about a pound of body fat and gained a pound of lean mass, dropping about one-half percent body fat (measured using the Bod Pod, a very cool device). The control group gained a few ounces of fat and lost a couple ounces of lean mass in comparison, gaining 0.3 percent body fat in the process.

The Cortisol Connection


Fish oil may cause fat loss by decreasing cortisol- a stress hormone linked to fat gain. The test subjects lost fat, despite no changes in the rate of calorie or fat burning. The research team discovered that the fish oil reduced cortisol, which decreased fat storage, increased the release of stored fat, and preserved metabolically active muscle tissue. The omega-3 fatty acids DHA and EPA in fish oil improved body composition by decreasing cortisol levels.

The researchers measured cortisol in saliva, which is only a rough measure of cortisol levels in blood, fat, or muscle. We need more thorough studies to find out why fish oil promotes fat loss. The bottom line is that fish oil has shown once again that it is effective for managing fat mass and body composition.

What is the take home message? Fish oil, either from Omega-3-rich fish or capsules, decrease fat mass and body weight and increasing muscle mass. This is in addition to the numerous health benefits in the brain, heart, blood vessels, and metabolism. It takes little effort to add fish oil to the diet or supplement pack, and is relatively inexpensive. Fish oil will not produce an overnight impact, and won't make you an instant winner on "The Biggest Loser" TV show. Daily fish oil supplements will eventually help you reach your goal, particularly when combined with exercise and a healthy diet.

References:

Dangour AD, Allen E, et al. Effect of 2-y n-3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: a randomized, double-blind, controlled trial. Am J Clin Nutr, 2010 Jun;91(6):1725-32.

Defilippis AP, Blaha MJ, et al. Omega-3 Fatty acids for cardiovascular disease prevention. Curr Treat Options Cardiovasc Med, 2010 Aug;12(4):365-80.

Delarue J, LeFoll C, et al. N-3 long chain polyunsaturated fatty acids: a nutritional tool to prevent insulin resistance associated to type 2 diabetes and obesity? Reprod Nutr Dev, 2004 May-Jun;44(3):289-99.

Björntorp P, Rosmond R. Obesity and cortisol. Nutrition, 2000 Oct;16(10):924-36.

Couet C, Delarue J, et al. Effect of dietary fish oil on body fat mass and basal fat oxidation in healthy adults. Int J Obes Relat Metab Disord, 1997 Aug;21(8):637-43.

Hill AM, Buckley JD, et al. Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. Am J Clin Nutr, 2007 May;85(5):1267-74.

Thorsdottir I, Tomasson H, et al. Randomized trial of weight-loss-diets for young adults varying in fish and fish oil content. Int J Obes, 2007 Oct;31(10):1560-6.
Noreen EE, Sass MJ, et al. Effects of supplemental fish oil on resting metabolic rate, body composition, and salivary cortisol in healthy adults. J Int Soc Sports Nutr, 2010 Oct 8;7:31.

среда, 12 марта 2014 г.

почему принимать аспирин и парацетамол опасно?

  

На заметку: почему принимать аспирин и парацетамол опасно?
1. Таблетка «от головы»
В большинстве случаев, почувствовав легкое недомогание или головную боль, мы принимаем какой-нибудь «Эффералган» или «Колдрекс» на ночь в надежде на то, что утром проснемся здоровыми и пойдем на работу или в спортзал. Делать так абсолютно неправильно.

Начнем с того, что эти вещества даже теоретически неспособны вылечить простуду, а продолжим тем, что негативные эффекты парацетамола и аспирина давно и широко известны, но в силу дешевизны эти лекарства продолжают продаваться большими объемами.

2. Парацетамол
Профессионалы говорят, что сегодня парацетамол не получил бы допуска в качестве рецептурного препарата, не говоря уже о свободной продаже. Даже разрешенная суточная доза (4 грамма) может вызвать тяжелое отравление и токсическое поражение печени.

Двукратное превышение этой дозы чревато острой печеночной недостаточностью, приводящей к мучительной смерти, длящейся несколько суток. Другими словами, кажущиеся безвредными таблетки способны серьезно подорвать здоровье или даже убить.

3. Аспирин
Обезболивающее действие аспирина (ацетилсалициловой кислоты) длится всего несколько часов, а эффект разжижения крови — несколько суток. Это способно привести к тому, что может открыться и начать кровоточить затянувшаяся царапина или ранка во рту после визита к зубному.

Некоторые «врачи» рекомендуют принимать аспирин в качестве профилактики атеротромбоза, коронарной болезни сердца или даже снижения риска развития рака. Но исследования показывают, что эта рекомендация оправдана только для тех, кто уже перенес инсульт.

4. Препараты от простуды
Большая часть препаратов от простуды — «Колдрекс», «Терафлю», «Фервекс» – это всего лишь парацетамол, небольшая доза аскорбиновой кислоты, а также препарат, устраняющий насморк. В составе нет никаких компонентов, способных вылечить или приостановить болезнь.

Использовать эти препараты для облегчения состояния вредно, а при ряде условий и просто опасно. Ну а традиционная практика принимать такие препараты на ночь вредна вдвойне, так как парацетамол и подобные вещества негативно влияют на обмен веществ.

5. Обезболивающие и гормональный уровень
Любые нестероидные противовоспалительные препараты, такие как аспирин, ибупрофен, кетопрофен, диклофенак и другие, негативно влияют на синтез одного из важнейших гормонов для роста мышц – гормона роста.

Учитывая то, что даже одна таблетка простого аспирина может оказывать воздействие на организм в течение нескольких суток, говорить о серьезных силовых тренировках в это время нельзя. И уж тем более нельзя выпивать "Колдрекс" и идти в зал.

6. "Алка-Зельтцер" и снятие похмелья
Состав популярного препарата для борьбы с похмельным синдромом – обычный аспирин, пищевая сода и лимонная кислота. Аспирин обезболивает, пищевая сода снижает кислотность в желудке, возникшую от приема алкоголя, аспирина и лимонной кислоты.

«Алка-Зельтцер» не лечит похмелье, и тем более не может использоваться как профилактическое средство для облегчения дальнейшего состояния. Если Вы и так «отравили» свой организм алкоголем, не нужно его добивать опасными и устаревшими обезболивающими.

7. Безопасные обезболивающие
Европейские специалисты чаще всего рекомендуют ибупрофен («Нурафен», «МИГ400», «Адвил», «Солпафлекс» и другие) в качестве замены устаревших и опасных аспирина и парацетамола. Это вещество снимает головную боль и высокую температуру.

Но нужно всегда помнить, что любые обезболивающие способны вызвать желудочное кровотечение или причинить другой вред организму, и их применение должно быть оправданным. Пить их «от простуды» или «от головы» уж точно не стоит.

понедельник, 10 марта 2014 г.

High-thiamine diet reduces chance of depression

Yesterday we wrote about an experiment done in the 1990s in which a supplement containing 50 mg thiamine – alias vitamin B1 – improved the mood of the student subjects. In 2012 Chinese epidemiologists published a study with similar results to those of the experiment done in the nineties. The Chinese suggest that a diet containing relatively large amounts of thiamine reduces the likelihood of depression.

A few days ago we wrote about an experiment done in the 1990s in which a supplement containing 50 mg thiamine – alias vitamin B1 – improved the mood of the student subjects. In 2012 Chinese epidemiologists published a study with similar results to those of the experiment done in the nineties. The Chinese suggest that a diet containing relatively large amounts of thiamine reduces the likelihood of depression.
The researchers, who worked at the Shanghai Institutes for Biological Sciences, studied 1587 men and women aged between 50 and 70. The researchers used questionnaires to determine whether the participants had depressive tendencies.
The researchers also measured the amount of thiamine the participants ingested through their diet, and analysed the composition of the participants’ red blood cells. They looked not only at the concentration of free thiamine, but also at that of thiamine monophosphate and thiamine diphosphate. The latter in particular plays a key role in depression: it’s a co-factor for the production of serotonin.
The researchers divided the participants into four equal-sized quartiles according to their blood levels and the amount of dietary thiamine they ingested. In the figures below the values for thiamine intake and status are lowest for quartile 1 and highest for quartile 4.
The researchers fixed the likelihood of depression in the participants with the highest thiamine intake [Q4] at 1. The figure below shows that the participants with the lowest thiamine intake were one and a half times more likely to suffer from depression.
1
The relationship was not statistically significant, though. This is probably because the level of thiamine intake doesn’t actually tell us that much.
The body uses most of the thiamine it ingests – in the form of thiamine diphosphate – to convert glucose into energy. That means that you really need to look at the relationship between thiamine intake and carbohydrate intake. When the Chinese did this, they discovered that, among the participants, a high carbohydrate intake coincided with a high thiamine intake. That’s why they couldn’t see a relationship between thiamine intake and likelihood of depression.
The figures below are more revealing. The subjects in the quartile with the lowest concentrations of free thiamine, thiamine monophosphate and thiamine diphosphate in their red blood cells were 3, 3.5 and 2 times respectively more likely to be depressed than those in the quartile with the highest concentration. And yes, the relationships were statistically significant.
The relationship was not statistically significant, though. This is probably because the level of thiamine intake doesn’t actually tell us that much.
The body uses most of the thiamine it ingests – in the form of thiamine diphosphate – to convert glucose into energy. That means that you really need to look at the relationship between thiamine intake and carbohydrate intake. When the Chinese did this, they discovered that, among the participants, a high carbohydrate intake coincided with a high thiamine intake. That’s why they couldn’t see a relationship between thiamine intake and likelihood of depression.
The figures below are more revealing. The subjects in the quartile with the lowest concentrations of free thiamine, thiamine monophosphate and thiamine diphosphate in their red blood cells were 3, 3.5 and 2 times respectively more likely to be depressed than those in the quartile with the highest concentration. And yes, the relationships were statistically significant.
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Going by the results of this study you’d expect that taking thiamine supplements would reduce the likelihood of depression. But there were too few supplement users among the participants to be able to say whether this was indeed the case.
“This population-based analysis suggests an association between thiamine malnutrition and depressive symptoms among older Chinese adults”, is the researchers’ careful formulation. “This finding warrants further investigation in prospective studies.”

Thiamine nutritional status and depressive symptoms are inversely associated among older Chinese adults.

Zhang G1, Ding H, Chen H, Ye X, Li H, Lin X, Ke Z.
Abstract
Thiamine has been hypothesized to play an important role in mental health; however, few studies have investigated the association between thiamine nutritional status and depression in the general population. Concentrations of free thiamine and its phosphate esters [thiamine monophosphate (TMP) and thiamine diphosphate (TDP)] in erythrocytes were measured by HPLC among 1587 Chinese men and women aged 50-70 y. The presence of depressive symptoms was defined as a Center for Epidemiological Studies Depression Scale score of ?16. The median erythrocyte concentration (nmol/L) was 3.73 for free thiamine, 3.74 for TMP, and 169 for TDP. The overall prevalence of depressive symptoms was 11.3%. Lower concentrations of all 3 erythrocyte thiamine biomarkers were monotonically associated with a higher prevalence of depressive symptoms: the multivariable adjusted ORs comparing the lowest with the highest quartiles were 2.97 (95% CI = 1.87, 4.72; P-trend < 0.001) for free thiamine, 3.46 (95% CI = 1.99, 6.02; P-trend < 0.001) for TMP, and 1.98 (95% CI = 1.22, 3.21; P-trend = 0.002) for TDP. In conclusion, poorer thiamine nutritional status and higher odds of depressive symptoms were associated among older Chinese adults. This finding should be further investigated in prospective or interventional studies.
PMID: 23173173 [PubMed - indexed for MEDLINE] PMCID: PMC3521461

Whey only counteracts growth-reducing effect of alcohol a little

If you drink alcohol [structural formula on the right] after a training session it gets in the way of the anabolic processes taking place. Drinking a protein shake after the training session reduces this damage, but doesn’t get rid of it completely, write Australian sports scientists from RMIT University in PLoS One.

If you drink alcohol [structural formula on the right] after a training session it gets in the way of the anabolic processes taking place. Drinking a protein shake after the training session reduces this damage, but doesn’t get rid of it completely, write Australian sports scientists from RMIT University in PLoS One.
Lychees contain polyphenols such as cyanidin-3-rutinoside [structural formula shown below], cyanidin-glucoside, quercetin-3-rutinoside (better known as rutin) and quercetin-glucoside. [J Agric Food Chem. 2000 Dec;48(12):5995-6002.] Asian researchers have published regularly on the positive health effects of phenol-rich lychee extracts over the past six years.
If you drink alcohol after doing weight training, your muscles take longer to recover. That’s partly because alcohol deactivates testosterone.
Nevertheless, a lot of athletes drink alcohol after training. The researchers were curious to know to what extent post-workout whey supplementation could help to cancel out the anti-anabolic effect of alcohol.
The researchers got eight active men to do strength training leg exercises and then several cardio sessions on a cyclometer. The researchers put the cardio sessions together in such a way that the total workout model allowed for all imaginable types of training regimes.
An hour after finishing their training the men drank the equivalent of 12 units of alcohol. On one occasion the subjects were given 25 g maltodextrin after their workout, and 25 g maltodextrin four hours after the workout, when they had stopped drinking.
On another occasion the subjects were given two 25-g doses of whey instead of maltodextrin.
Alcohol inhibited protein synthesis, the researchers observed when they examined samples of the men’s muscle fibre. Whey [ALC-PRO] reduced this effect, but was not capable of restoring muscle fibre synthesis to the level achieved by drinking a whey shake but not drinking alcohol after training [PRO].
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Post-training alcohol consumption had virtually no effect on the amount of amino acids that reached the muscle cells. What it did do was to reduce the activity of anabolic signalling molecules like mTOR and p70S6K in the muscle cells.
“In conclusion, the current data provide the novel observation that alcohol impairs the response of muscle protein synthesis in exercise recovery in human skeletal muscle despite optimal nutrient provision”, the researchers write. “The quantity of alcohol consumed in the current study was based on amounts reported during binge drinking by athletes.”
“We propose our data is of paramount interest to athletes and coaches. Our findings provide an evidence-base for a message of moderation in alcohol intake to promote recovery after exercise with the potential to alter current sports culture and athlete practices.”

Alcohol Ingestion Impairs Maximal Post-Exercise Rates of Myofibrillar Protein Synthesis following a Single Bout of Concurrent Training.

Abstract
INTRODUCTION:
The culture in many team sports involves consumption of large amounts of alcohol after training/competition. The effect of such a practice on recovery processes underlying protein turnover in human skeletal muscle are unknown. We determined the effect of alcohol intake on rates of myofibrillar protein synthesis (MPS) following strenuous exercise with carbohydrate (CHO) or protein ingestion.
METHODS:
In a randomized cross-over design, 8 physically active males completed three experimental trials comprising resistance exercise (8×5 reps leg extension, 80% 1 repetition maximum) followed by continuous (30 min, 63% peak power output (PPO)) and high intensity interval (10×30 s, 110% PPO) cycling. Immediately, and 4 h post-exercise, subjects consumed either 500 mL of whey protein (25 g; PRO), alcohol (1.5 g·kg body mass(-1), 12±2 standard drinks) co-ingested with protein (ALC-PRO), or an energy-matched quantity of carbohydrate also with alcohol (25 g maltodextrin; ALC-CHO). Subjects also consumed a CHO meal (1.5 g CHO·kg body mass(-1)) 2 h post-exercise. Muscle biopsies were taken at rest, 2 and 8 h post-exercise.
RESULTS:
Blood alcohol concentration was elevated above baseline with ALC-CHO and ALC-PRO throughout recovery (P<0.05). Phosphorylation of mTOR(Ser2448) 2 h after exercise was higher with PRO compared to ALC-PRO and ALC-CHO (P<0.05), while p70S6K phosphorylation was higher 2 h post-exercise with ALC-PRO and PRO compared to ALC-CHO (P<0.05). Rates of MPS increased above rest for all conditions (?29-109%, P<0.05). However, compared to PRO, there was a hierarchical reduction in MPS with ALC-PRO (24%, P<0.05) and with ALC-CHO (37%, P<0.05).
CONCLUSION:
We provide novel data demonstrating that alcohol consumption reduces rates of MPS following a bout of concurrent exercise, even when co-ingested with protein. We conclude that alcohol ingestion suppresses the anabolic response in skeletal muscle and may therefore impair recovery and adaptation to training and/or subsequent performance.
PMID: 24533082 [PubMed - in process] PMCID: PMC3922864